Welcome to MethylDetect

We make ready-to-use DNA Methylation Assays

Welcome to MethylDetect

We make ready-to-use DNA Methylation Assays

We offer ready-to-use assays, custom-tailored services, bisulfite modification kits, and real-time PCR master mix. Read about our services here:

EpiMelt Methylation Detection Assays

 

Cost-effective

Fast and robust

User friendly

EpiMelt Methylation Detection Assays

 

Cost-effective
Fast and robust
User friendly

EpiMelt Real-Time PCR Master Mix

 

Optimized for EpiMelt Methylation Detection Assays

High sensitivity

Robust across platforms

 

EpiMelt Real-Time PCR Master Mix

 

Optimized for EpiMelt Methylation Detection Assays

High sensitivity

Robust across platforms

EpiMelt Bisulfite Modification Kits

 

High efficiency

Easy and reliable

EpiMelt Bisulfite Modification Kits

 

High efficiency

Easy and reliable

MethylDetect introduces:

DNA Methylation is one of the most widely studied epigenetic mechanisms of gene expression regulation.

Aberrant methylation of increasing number of genes is being shown to contribute to the majority of diseases such as cancer, cardiovascular disorders, aging, obesity, allergy, diabetes, depression, Alzheimer’s, Parkinson’s or schizophrenia.

 

 

Read more

Solid research evidence already shows that DNA methylation-based biomarkers can be utilized at all stages of clinical disease management including:

  • Disease risk assessment
  • Early detection
  • Personalization of treatment
  • Monitoring of chronic disorders and recurrence

The technology is already in use for detection of DNA methylation biomarkers in fields like forensics, and for investigating challenging DNA materiel sources as liquid biopsies and FFPE tissues.

MethylDetect offers ready-to-use kits for detection of aberrant gene methylation. The kits are based on the MS-HRM (Methylation Sensitive High Resolution Melting) technology and can be used with standard laboratory equipment. Additionally, our new controls system shipped with each kit, provides state-of-the-art experimental reliability.

methyldetect pipettes

Assay Specific Control System

Designed to ensure optimal measurement of methylation. Applicable to the majority of methylation screening technologies.
Generation of standard curves for technologies such as q-MSP or MethyLight.

 

DNA Methylation detection using the EpiMelt kit

 

 

1. ADD

The MethylDetect kit components and the bisulfite modified biological samples to the PCR reagents

 

 

1. AMPLIFY

Use a standard laboratory Real Time-PCR system to PCR amplify the target

 

 

3. DETECT

Assess the methylation status of the sequence of interest with a High-Resolution Melting Module

 

 

Get in touch

Please contact us if you have questions about our company, our products, or general enquiries.
Please use the form below.

 

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Get in touch

Please contact us if you have questions about our company, our products, or general enquiries.
Please use the form below.